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Barrier Defense Function of the Small Intestine: Effect of Ethanol and Acute Burn Trauma

  • E. A. Carter
  • P. R. Harmatz
  • J. N. Udall
  • W. A. Walker
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 216 A)

Abstract

Nonspecific barriers to the passage of infectious and/or potentially toxic macromolecules exist in the small intestine. They include the “unstirred water layer,” a zone of retarded diffusion which would slow the movement of macromolecules toward the mucosal epithelium; a layer of intestinal mucus which would interfere with macromolecule penetration; and finally, the glycocalyx, anchored in the plasmalemma of the epithelial cell (1).

Keywords

Small Intestine Horse Radish Peroxidase Intestinal Mucus Unstirred Water Layer Small Intestinal Permeability 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • E. A. Carter
    • 1
    • 2
  • P. R. Harmatz
    • 1
    • 2
  • J. N. Udall
    • 1
    • 2
  • W. A. Walker
    • 1
    • 2
  1. 1.Combined Gastroenterology and Nutrition Unit, Children’s Hospital, Shriner Burns HospitalMassachusetts General HospitalBostonUSA
  2. 2.Harvard Medical SchoolBostonUSA

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