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Endocrine Regulation of the Ocular Secretory Immune System

  • D. A. Sullivan
  • L. E. Hann
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 216 A)

Abstract

Past research has demonstrated that androgens stimulate the accumulation of both IgA and secretory component (SC) in tears of rats (1,2). This hormone action appears to be due to an enhancement of the synthesis and/or secretion of IgA and SC by the lacrimal gland (2,3) and seems to underly the sexual dimorphism known to exist in the ocular secretory immune system (1–4). However, whether this hormonal effect is unique to the eye or is shared by other mucosal sites has not been determined.

Keywords

Pituitary Gland Lacrimal Gland Respiratory Secretion Secretory Component Mucosal Site 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • D. A. Sullivan
    • 1
    • 2
  • L. E. Hann
    • 1
    • 2
  1. 1.Department of OphthalmologyHarvard Medical SchoolBostonUSA
  2. 2.the Immunology UnitEye Research InstituteBostonUSA

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