Induction of Proliferative and Destructive Graft-Versus-Host Reactions in the Small Intestine
Local cell mediated immunity (CMI) is a feature of certain intestinal diseases, including food sensitive enteropathies (FSE) and these disorders exhibit a similar pattern of villus atrophy, crypt hyperplasia and lymphocytic infiltration of the epithelium (1). Although the mucosal pathology shows both hyperplastic and destructive features, the underlying basis of the different changes is not fully understood.
KeywordsNatural Killer Natural Killer Activity Irradiate Mouse Intestinal Phase Crypt Hyperplasia
Unable to display preview. Download preview PDF.
- 1.Mowat, A.McI., in Local Immune Response of the Gut, CRC Press, 199, 1984.Google Scholar
- 2.Mowat, A.McI., Tait, R.C., Mackenzie, S., Davies, M.D.J, and Parrott, D.M.V., Clin. Exp. Immunol. 52, 19, 1983.Google Scholar
- 7.Mowat, A.McI., Transplantation, 1987 (in press).Google Scholar
- 8.van Elven, E.H., Rolink, A.G., van der ween, F. and Gleichman, E., J. Exp. Med. 153, 1474, 1981.Google Scholar