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T Cell and Mononuclear Phagocyte Populations of the Human Small and Large Intestine

  • L. K. Trejdosiewicz
  • G. Malizia
  • S. Badr-el-Din
  • C. J. Smart
  • D. J. Oakes
  • J. Southgate
  • P. D. Howdle
  • G. Janossy
  • L. W. Poulter
  • M. S. Losowsky
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 216 A)

Abstract

Considering the diverse roles subsumed by the intestinal mucosal immune system, namely defense against potential luminal pathogens and maintenance of immune tolerance to dietary antigens, our knowledge of the local adaptations of immunocyte subpopulations remains sparse. In the past few years, the range of monoclonal antibodies to lymphocyte and mononuclear phagocyte (Mph) surface differentiation antigens has greatly increased. Such reagents, often shown capable of distinguishing between functional cell subpopulations, should therefore provide potent tools for the in situ analysis of the gut mucosal immune system.

Keywords

Lamina Propria Mononuclear Phagocyte Lymphoid Follicle Mucosal Immune System Lymphoid Aggregate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • L. K. Trejdosiewicz
    • 1
  • G. Malizia
    • 1
  • S. Badr-el-Din
    • 1
  • C. J. Smart
    • 1
  • D. J. Oakes
    • 1
  • J. Southgate
    • 1
  • P. D. Howdle
    • 1
  • G. Janossy
    • 1
    • 2
  • L. W. Poulter
    • 1
    • 2
  • M. S. Losowsky
    • 1
  1. 1.Departments of Medicine, St. James’s University HospitalUniversity of LeedsLeedsUK
  2. 2.Academic Department of Immunology, Royal FreeHospital Medical SchoolLondonUK

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