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Rabbit IgA Heavy Chain Genes: Cloning and In Vitro Expression

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Recent Advances in Mucosal Immunology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 216 A))

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Abstract

Southern blot analysis of rabbit germline DNA showed the rabbit genome contained at least 10 Ca genes (1). This observation was of particular interest since both mouse and human have only one and two Ca genes, respectively. Genomic blot data are consistent with studies of rabbit IgA heavy chain allotypes which suggested the existence of multiple IgA isotypes (2–4), To further examine the complexity and genetic control of rabbit IgA, we have undertaken molecular and genetic studies of the IgA heavy chains.

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References

  1. Knight, K.L., Burnett, R.C. and McNicholas, J.M., J. Immunol. 134, 1245, 1985.

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Author information

Authors and Affiliations

  1. Department of Microbiology and Immunology, University of Illinois College of Medicine at Chicago, Chicago, IL, USA

    R. C. Burnett, R. D. Schneiderman & K. L. Knight

Authors
  1. R. C. Burnett
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  2. R. D. Schneiderman
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  3. K. L. Knight
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Editor information

Editors and Affiliations

  1. University of Alabama at Birmingham, Birmingham, Alabama, USA

    Jiri Mestecky  & Jerry R. McGhee  & 

  2. McMaster University, Hamilton, Ontario, Canada

    John Bienenstock

  3. State University of New York at Buffalo, Buffalo, New York, USA

    Pearay L. Ogra

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© 1987 Plenum Press, New York

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Burnett, R.C., Schneiderman, R.D., Knight, K.L. (1987). Rabbit IgA Heavy Chain Genes: Cloning and In Vitro Expression. In: Mestecky, J., McGhee, J.R., Bienenstock, J., Ogra, P.L. (eds) Recent Advances in Mucosal Immunology. Advances in Experimental Medicine and Biology, vol 216 A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5344-7_3

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  • DOI: https://doi.org/10.1007/978-1-4684-5344-7_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5346-1

  • Online ISBN: 978-1-4684-5344-7

  • eBook Packages: Springer Book Archive

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