Nicotinic Acetylcholine Receptor and Myasthenia Gravis Studied by Anti-Receptor Monoclonal Antibodies

  • Socrates J. Tzartos
Part of the NATO ASI Series book series (NSSA, volume 133)


Antibodies to the nicotinic acetylcholine receptor (AChR) cause the disease myasthenia gravis (MG). Both the molecule and the disease have been extensively studied and serve as models for similar systems. Monoclonal antibodies (mAbs) to the AChR have been used for several years as probes for the study of the AChR and the MG. In the introduction, some general information will be presented on the AChR, the disease and the mAbs.


Acetylcholine Receptor Nicotinic Acetylcholine Receptor Electric Organ Antigenic Modulation AChR Subunit 
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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Socrates J. Tzartos
    • 1
  1. 1.Dep. Biochem.Hellenic Pasteur InstituteAthensGreece

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