Applications of Animal Embryo Culture Research to Human IVF and Embryo Transfer Programs
The motivation for many reproductive biologists to study early developmental processes is the specter of overpopulation. The figures are grim; for example, India is estimated to have a billion inhabitants by the year 2000. Similarly, birth rates remain extremely high throughout Africa, a continent that is facing continual shortfalls in food production. However, the other side of the coin is the problem of infertility. In traditional societies, particularly those of Asia and Africa, a childless woman is the object of scorn and pity. Even in Western societies where adoption has been common, the combination of increased rates of infertility and the difficulty of finding appropriate adoptive babies has exacerbated the problems of the childless couple. Thus, many reproductive biologists have come to realize that although the global imperative of halting population growth is still of paramount importance, the individual right to reproduction must be recognized, and in cases of infertility, ameliorated in so far as is possible. Furthermore, the study of normal processes, albeit in vitro, may lead to important new insights regarding in vivo early reproductive processes, and enhance our ability to develop new and acceptable contraceptive techniques.
KeywordsMouse Embryo Fallopian Tube Preimplantation Embryo Human Oocyte Childless Woman
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- Bavister, B.D., 1981, Analysis of culture media for in vitro fertilization and criteria for success, in: Fertilization and Embryonic Development in vitro (L. Mastroianni, Jr., and J.D. Biggers, eds.), Plenum Press, New York, pp. 41–60.Google Scholar
- Brinster, R.L., 1972, Cultivation of the mammalian egg, in: Growth, Nutrition and Metabolism of Cells in Culture, Volume II (G. Rothblat, and V. Cristofalo, eds.), Academic Press, New York, pp. 251–286.Google Scholar
- Dandekar, P.V., Spindle, A.I., Martin, M.C., and Glass, R.H., 1985, Development of mouse embryos in five different media, Fertil. Steril. 41: 61S (abs. no, 142).Google Scholar
- Hewitt, J., Cohen, J., Krishnaswamy, V., Fehilly, C.B., Steptoe, P.C., and Walters, D.E., 1985, Treatment of idiopathic infertility, cervical mucus hostility, and male infertility: artificial insemination with husband’s semen or in vitro fertilization? Fertil. Steril. 44: 350–355.PubMedGoogle Scholar
- Hunter, R.H.F., 1980, Physiology and Technology of Reproduction in Female Domestic Animals, Academic Press, London, pp. 214–218.Google Scholar
- Kline, J., and Stein, Z., 1985, Very early pregnancy, in: Reproductive Toxicology (R.L. Dixon, ed.), Raven Press, New York, pp. 251–265.Google Scholar
- Smith, A.U., 1953, In vitro experiments with rabbit eggs, in: Mammalian Germ Cells (Ciba Foundation Symposium) (G.E.W. Wolstenholme, ed.), Churchill, London, pp. 217–232.Google Scholar