In Vitro Growth of Non-Human Primate Pre- and Peri- Implantation Embryos

  • Dorothy E. Boatman


The close phylogenetic relationship between man and non-human primates has made these animals, especially the rhesus monkey, of particular interest for scientific research. However, since the early pioneer work (Hartman and Corner, 1941; Heuser and Streeter, 1941; Lewis and Hartman, 1941), only a few investigators have studied preimplantation embryology in non-human primates. A major reason for this situation is the expense of maintaining these long-lived animals (at least 30 years in captivity), which are largely monotocous and normally yield relatively few embryos in each reproductive season (albeit females may have as many as 18 reproductive seasons [years]). Additionally, some standard animal research procedures that would curtail the fertility of the animals (e. g., the excision of oviducts for ova/embryo flushing) may be contraindicated by the goals of breeding programs that have been established to maintain adequate supplies of these animals. In the past, the scarcity of non-human primate embryos has tended to obviate their clear appropriateness as models for the study of early human development. Recent advances in the techniques of super-stimulation of follicular growth, in vitro fertilization (IVF) and embryo culture have increased the supply of non-human primate embryos (Bavister et al., 1983a; Boatman and Bavister, 1984; Boatman et al., 1986; Balmaceda et al., 1984).


Rhesus Monkey Embryo Transfer Oocyte Maturation Zona Pellucida Embryo Culture 


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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Dorothy E. Boatman
    • 1
  1. 1.Wisconsin Regional Primate Research CenterUniversity of WisconsinMadisonUSA

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