Somatostatin pp 169-182 | Cite as

Physiological Significance of Somatostatin in Growth Hormone Regulation

  • Gloria Shaffer Tannenbaum
Part of the Serono Symposia, USA book series (SERONOSYMP)


The secretion of growth hormone (GH) is pulsatile in nature in every species examined thus far. Particularly in the rat, GH secretion is characterized by a striking ultradian rhythm (1), with high-amplitude GH secretory bursts occurring at precise 3.3 hour intervals throughout a 24-hour period; in the intervening trough periods basal plasma GH levels are undetectable (Fig. 1).


Growth Hormone Growth Hormone Secretion Growth Hormone Release Factor Ultradian Rhythm Plasma Growth Hormone Level 
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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Gloria Shaffer Tannenbaum
    • 1
    • 2
  1. 1.Neuropeptide Physiology LaboratoryMcGill UniversityMontrealCanada
  2. 2.Montreal Children’s Hospital Research Institute and the Departments of Pediatrics, Neurology and NeurosurgeryMcGill UniversityMontrealCanada

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