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Early Events in Lymphocyte Activation Triggered Via CD3/Ti or CD2

  • P. C. L. Beverley
  • D. L. Wallace
  • K. O’Flynn
  • D. C. Linch
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 213)

Abstract

In recent years considerable insight has been gained into the sequence of events necessary for activation of lymphocytes. Several techniques have contributed to this progress; in particular the use of monoclonal cell populations, monoclonal antibodies to defined surface molecules and novel assays for detecting early events consequent on ligand binding has allowed the definition of several surface molecules of lymphocytes which can transmit signals to the cell and a variety of biochemical events which occur following ligand binding. Nevertheless many questions remain unresolved.

Keywords

Phorbol Myristate Acetate Phorbol Myristate Acetate Accessory Cell Peripheral Blood Mononuclear Follow Ligand Binding 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • P. C. L. Beverley
    • 1
  • D. L. Wallace
    • 1
  • K. O’Flynn
    • 2
  • D. C. Linch
    • 2
  1. 1.ICRF Human Tumour Immunology Group, Faculty of Clinical SciencesUniversity CollegeLondonUK
  2. 2.Department of Haematology, Faculty of Clinical SciencesUniversity CollegeLondonUK

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