Induction of the Glucokinase-Glucose Sensor in Pancreatic Islets of Insulinoma-Bearing Rats Following Tumor Removal

  • F. J. Bedoya
  • M. C. Appel
  • R. Goberna
  • F. M. Matschinsky
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 211)


Blood glucose concentrations in mammals are maintained within a narrow range because the glucose homeostat in the organism controls glucose storage and usage by a variety of cells.


Islet Cell Pancreatic Islet Hexokinase Activity Phosphoglucose Isomerase Islet Tissue 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • F. J. Bedoya
    • 1
  • M. C. Appel
    • 2
  • R. Goberna
    • 1
  • F. M. Matschinsky
    • 3
  1. 1.Departamento de BioquimicaFacultad de MedicinaSevillaSpain
  2. 2.Department of Pathology, Medical CenterUniversity of MassachusettsWorcesterUSA
  3. 3.Diabetes Center and the Department of Biochemistry and Biophysics, School of MedicineUniversity of PennsylvaniaPhiladelphiaUSA

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