Calcium Regulation of Membrane Fusion during Hormone Secretion
Calcium is only one of a number of second messengers that are becoming increasingly implicated in processes regulating hormone secretion by exocytosis. The most completely studied calcium-dependent secretory system is the chromaffin cell from the adrenal medulla, a system with many operational similarities to the insulin secreting β-cell from islets of Langerhans. Inasmuch as we have had the opportunity to compare these two systems in detail we will attempt to make a number of hopefully interesting comparisons between data obtained from the chromaffin cell and certain data of relevance from the β-cell system.
KeywordsArachidonic Acid Chromaffin Cell Membrane Fusion Adrenal Medulla Inositol Phosphate
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