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Glucose-Evoked Changes in [K+] and [Ca2+] in the Intercellular Spaces of the Mouse Islet of Langerhans

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Biophysics of the Pancreatic β-Cell

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 211))

Abstract

Microelectrode studies of the glucose-evoked burst pattern of electrical activity in pancreatic β-cells have indicated that the underlying mechanism involves the cyclic activation of K-channels.4,5,9,11,32 Furthermore, it is well documented that the action potentials during the bursts result from the activation of two voltage-gated membrane channels, Ca-channels7,8,25,31,34 and K-channels.

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Authors and Affiliations

  1. Laboratory of Cell Biology and Genetics, NIDDK, National Institutes of Health, Bldg 8, Rm. 403, Bethesda, MD, 20892, USA

    E. Perez-Armendariz & I. Atwater

Authors
  1. E. Perez-Armendariz
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  2. I. Atwater
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Editor information

Editors and Affiliations

  1. National Institutes of Health, Bethesda, Maryland, USA

    Illani Atwater  & Eduardo Rojas  & 

  2. University of Alicante, Alicante, Spain

    Bernat Soria

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© 1986 Plenum Press, New York

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Perez-Armendariz, E., Atwater, I. (1986). Glucose-Evoked Changes in [K+] and [Ca2+] in the Intercellular Spaces of the Mouse Islet of Langerhans. In: Atwater, I., Rojas, E., Soria, B. (eds) Biophysics of the Pancreatic β-Cell. Advances in Experimental Medicine and Biology, vol 211. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5314-0_3

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  • DOI: https://doi.org/10.1007/978-1-4684-5314-0_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5316-4

  • Online ISBN: 978-1-4684-5314-0

  • eBook Packages: Springer Book Archive

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