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Insulin Secretion Studied in Islets Permeabilised by High Voltage Discharge

  • P. M. Jones
  • S. L. Howell
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 211)

Abstract

Studies of the cellular mechanisms of insulin secretion from intact β-cells are hampered, to some extent, by the existence of an intact plasma membrane which limits the degree to which the intracellular environment can be experimentally manipulated. One means of circumventing this problem is to permeabilise the plasma membrane of the β-cells by a high voltage discharge technique.

Keywords

Insulin Secretion Insulin Release Phorbol Ester Secretory Response High Voltage Discharge 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • P. M. Jones
    • 1
  • S. L. Howell
    • 1
  1. 1.Department of Physiology, King’s College London (KQC)University of LondonKensington, LondonEngland

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