Calcium and Potassium Currents Recorded from Pancreatic β-Cells Under Voltage Clamp Control

  • G. Trube
  • P. Rorsman
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 211)


It has been known for over 15 years that glucose and most other stimuli for insulin secretion induce electrical activity in the pancreatic β-cell4. The secretory and electrical responses are furthermore known to be closely correlated13. From membrane potential recordings obtained with conventional intracellular electrodes and from flux measurements at least three types of currents have been postulated10.


Outward Current Pipette Solution Bovine Chromaffin Cell Spontaneous Action Potential Depolarize Voltage Step 


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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • G. Trube
    • 1
  • P. Rorsman
    • 1
  1. 1.Max-Planck-Institut fur biophysikalische ChemieGottingenFederal Republic of Germany

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