New Views of Cell and Tissue Cytoarchitecture: Embedment-Free Electron Microscopy and Biochemical Analysis

  • Edward G. Fey
  • Sheldon Penman
Conference paper
Part of the NATO ASI Series book series (NSSA, volume 127)


Our perception of the cell interior is undergoing a fundamental change. What once appeared to be formless plasms are now seen to contain highly organized structural scaffolds. Even the soluble proteins, those not a part of skeletal structures, are no longer considered free, but associated with the skeletal framework. The implications of these studies of cell structure are beginning to emerge. The end result will likely be a change in many of the paradigms of our science. As with most changes in paradigm, progress is halting and not without conflict.


Nuclear Matrice Transmission Electron Micrographs Nuclear Matrix Madin Darby Canine Kidney Madin Darby Canine Kidney Cell 


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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Edward G. Fey
    • 1
  • Sheldon Penman
    • 1
  1. 1.Department of BiologyMassachusetts Institute of TechnologyCambridgeUSA

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