Attempted Treatment of Motor Neuron Disease with N-Acetylcysteine and Dithiothreitol
N-acetylcysteine (NAC) and Dithiothreitol (DTT), two compounds that prevent experimental amyotrophic lateral sclerosis (ALS) in the vitamin C - deficient guinea pig, were given to patients with motor neuron disease (MND). These patients were accepted regardless of the stage of their illness, promised uninterrupted treatment, instructed to come for monthly out-patient visits, forbidden the use of the NAC-antagonists phenacetin and acetaminophen and left free to continue any other mode of attempted therapy.
KeywordsAmyotrophic Lateral Sclerosis Spinal Muscular Atrophy Motor Neuron Disease Motor Neuron Disease Stretch Reflex
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