Autoimmune Involvement in Motor Neurone Disease
The possibility of an autoimmune pathogenesis in motor neurone disease (MND) has been debated for many years with little consensus. However, recent evidence from different sources has served to redirect attention towards such an involvement. Thus, early findings of a serum-borne neurotoxic factor in MND patients[l] have been confirmed by Roisen et al., while Gurney and his colleagues[3,4] have reported the presence in MND sera of autoantibodies to a muscle-derived growth factor for spinal neurones.
KeywordsAmyotrophic Lateral Sclerosis Motor Neurone Disease Stimulation Index Spinal Neurone Spinal Cord Cell
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