Macromolecular Surface Interactions
  • Ralph L. Nachman
  • Roy L. Silverstein
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)


Thrombospondin is a versatile multifunctional glycoprotein with a widespread tissue distribution. By virtue of its remarkable affinity for multiple macromolecules, it serves as a focus of surface assembly of multiprotein complexes, and thus plays a role in aggregation as well as modulating proteolytic events in non-fibrin-containing environments.


Plasminogen Activator Leukocyte Elastase Proteolytic Event Widespread Tissue Platelet Membrane Glycoprotein 
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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Ralph L. Nachman
    • 1
  • Roy L. Silverstein
    • 1
  1. 1.Cornell University Medical CollegeNew YorkUSA

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