Assessment of the Hazard of Genetic Toxicity

  • Ronald W. Hart
  • David Brusick
Part of the Life Science Monographs book series (LSMO)


A variety of toxic substances have structural features that permit them to reach the genetic material, where they produce damage. If such damage is not satisfactorily repaired, serious consequences for the organism can ensue. The theoretical and empirical bases for this conclusion are summarized in this chapter.


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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Ronald W. Hart
    • 1
  • David Brusick
    • 2
  1. 1.National Center for Toxicological Research (HFT-1)JeffersonUSA
  2. 2.Division of Molecular ToxicologyHazelton LaboratoriesKensingtonUSA

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