Reorganization of Cytoskeleton
Cell division is a multistage reorganization of morphology in which alterations of cytoskeleton play the central role. Division, like reorganization of interphase cells, described in Chapter 7, is based on alteration of the assembly and distribution of cytoskeletal structures. There are, however, important differences between these two types of reorganization. Morphogenetic reorganization adapts the morphology of the interphase cell to its environment; the course of this reorganization is directed by external factors. In contrast, the course of cell division is directed by a strict internal program; external factors can only disturb this course.
KeywordsMitotic Cell Mitotic Spindle Interphase Cell Spindle Microtubule Contractile Ring
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- Cox, S. M., Rao, P. N., and Brinkley, B. P. (1979) Action of nitrous oxide and griseofulvin on microtubules and chromosome movement in dividing cells, in Effects of Drugs on Cell Nucleus (H. Busch, S. T. Crooke, and Y. Dascal, eds.). Academic Press, New York, pp. 521–549.Google Scholar
- Vandre, D. D., Kronebusch, P., and Borisy, G. G. (1984) Interphase-mitosis transition: Microtubule rearrangements in cultured cells and sea urchin eggs, in Molecular Biology of the Cytoskeleton (G. G. Borisy, D. W. Cleveland, and D. B. Murphy, eds.), Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, pp. 3–16.Google Scholar
- Brinkley, B. R., and Brenner, S. L. (1982) Chromosome movement: A mini-review, inAxoplasmic Transport (D. G. Weiss, ed.), Springer-Verlag, Berlin, Heidelberg, pp. 27–38.Google Scholar
- Cande, W. Z., McDonald, K., Wordeman, L., and Coltrin, D. (1985) In vitro anaphase spindle elongation using isolated diatom spindles. Cell Motil. 5:169–170.Google Scholar
- De Brabander, M., Geuens, G., De Mey, J., and Jonaiau, M. (1979) Light microscopic and ultra-structural distribution of immunoreactive tubulin in mitotic mammalian cells, Biol. Cell. 34:213–226.Google Scholar
- Hays, T. S., and Salmon, E. D. (1985) Poleward traction force on a kinetochore at metaphase is a product of the number of kinetochore microtubules and fiber length, J. Cell Biol. 101 (5,pt2):6a (abstr. 20).Google Scholar
- Paweletz, N., Mazia, D., and Finze, E-M. (1984) The centrosome cycle of sea urchin eggs, Exp. Cell Res. 152:47–65. Google Scholar
- Pickett-Heaps, J. D., and Spurck, T. P. (1982) Studies on kinetochore function in mitosis. 1. The effects of colchicine and cytochalasin on mitosis in the Hantzschia amphioxys, Eur. J. Cell Biol. 28:72–82.Google Scholar
- White, J. I. (1985) The astral relaxation theory of cytokinesis revisited, Bio Essays 2:267–272.Google Scholar