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Dysphoric Premenstrual Changes: Are They Related to Affective Disorders?

  • Uriel Halbreich
  • Jean Endicott

Abstract

Some investigators hope to study premenstrual changes (PMC) as a model for more severe affective disorders. The use of premenstrual depression as a model for affective disorder is supported by studies that have found: (1) a differential and positive relationship between premenstrual depressive changes and a lifetime diagnosis of affective disorder, as compared with a lifetime diagnosis of no mental disorder or some other mental disorders (Coppen, 1965; Diamond, Rubinstein, Dunner, & Fieve, 1976; Kashiwagi, McClure, Reich, & Wetzel, 1976; Schuckit, Daly, Herrman, & Hineman, 1975; Wetzel, Reich, McClure, & Wald, 1975); (2) that some women experience a depressive syndrome during the premenstrual period severe enough to seek treatment for the condition (reviewed by Halbreich & Endicott, 1985a); (3) that suicide attempts and admissions to psychiatric hospitals for depressive episodes are associated with the paramenstrual period (Abramowitz, Backer, & Freischer, 1982); and (4) that premenstrual exacerbation of depressive syndromes is seen in those with depressive disorders.

Keywords

Major Depressive Disorder Affective Disorder Major Depressive Disorder Premenstrual Syndrome Depressive Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Uriel Halbreich
    • 1
  • Jean Endicott
    • 2
  1. 1.Department of PsychiatrySUNYBuffaloUSA
  2. 2.New York Psychiatric InstituteNew YorkUSA

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