Water at Biomolecule Interfaces

  • Julia M. Goodfellow
  • P. Lynne Howell
  • Robert Elliott
Part of the NATO ASI Series book series (NSSA, volume 126)


The aims of this paper are (i) to review our knowledge of solvent structure obtained from crystallographic studies of proteins and nucleic acids and (ii) to discuss structural aspects of computer simulations intended to increase our understanding of aqueous hydration of macromolecules. I shall use results from both crystallography and computer simulations in order to present a unified view of the structure of hydrogen bonded water networks surrounding biomolecules.


Minor Groove Solvent Structure Water Network Potential Energy Function Crystal Hydrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Julia M. Goodfellow
    • 1
  • P. Lynne Howell
    • 1
  • Robert Elliott
    • 1
  1. 1.Department of CrystallographyBirkbeck CollegeLondonUK

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