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Aspects of Cholinergic Function in Amyotrophic Lateral Sclerosis

  • S.-M. Aquilonius
  • P.-G. Gillberg

Abstract

The degenerative changes in amyotrophic lateral sclerosis (ALS) are preferentially restricted to the cortico-spinal tracts and to the lower motor neurons. Based on this mysterious selectivity, numerous theories regarding the etiology have been put forward, but none has so far been conclusively proved. However, irrespective of etiology, progressive neuronal degeneration should be accompanied by a disturbance of neurotransmission at the synapses of the fiber tracts involved.

Keywords

Amyotrophic Lateral Sclerosis Motor Neuron Dorsal Horn Lower Motor Neuron Amyotrophic Lateral Sclerosis Case 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • S.-M. Aquilonius
    • 1
  • P.-G. Gillberg
    • 1
  1. 1.Department of Neurology, Akademiska sjukhusetUppsala UniversityUppsalaSweden

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