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Plant Elongases

  • Claude Cassagne
  • René Lessire
  • Jean-Jacques Bessoule
  • Patrick Moreau

Abstract

In the early sixties, several investigators demonstrated the elongation of liver microsomal fatty acids in the presence of malonyl-CoA, ATP and reducing equivalents in the form of NADPH and/or NADH (see for example, Lorch et al., 1963). Furthermore, elongation was shown to occur in the absence of ATP, provided that a fatty acyl-CoA was added to the reaction mixture (Nugteren, 1965). The general mechanism of microsomal fatty acid elongation was supposed to be similar to that of de novo synthesis: condensation of the preferred substrate to form a beta-ketone, reduction of the beta-ketone to a secondary alcohol, dehydration of the alcohol to form a trans-alpha-beta-double-bond and reduction of the double-bond. Besides this microsomal elongation, also observed in Brain (Bourre, 1980), a mitochondrial elongation has also been demonstrated (Wakil, 1961).

Keywords

Erucic Acid Fatty Acid Elongation Jojoba Seed Microsomal Fatty Acid Mitochondrial Elongation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Claude Cassagne
    • 1
  • René Lessire
    • 1
  • Jean-Jacques Bessoule
    • 1
  • Patrick Moreau
    • 1
  1. 1.Institut de Biochimie Cellulaire et NeurochimieCNRSBordeaux cedexFrance

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