A Preliminary Characterization of Plant Holo-Acyl Carrier Protein Synthase
Acyl Carrier Protein (ACP) is a central cofactor in the biosynthesis of fatty acids and complex acyl lipids (1). ACP and CoA have a common prosthetic group, 4′-phosphopantetheine, to which fatty acids and intermediates are attached as thioesters. Using an E. coli auxotroph, Alberts and Vagelos (2) interpreted their in vivo experimental findings as suggesting that during de novo synthesis of ACP the prosthetic group is donated by CoA.
KeywordsProsthetic Group Acyl Carrier Protein Stage Reaction Spinach Leave Liquid Scintillation Spectrometry
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