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Alterations in Thyroid Function Parameters Following Administration of Fatty Acids

  • Inder J. Chopra
  • Tien-Shang Huang
  • David H. Solomon
  • Guadalupe N. Chua Teco

Abstract

Recent studies suggest that a thyroid hormone binding inhibitor (THBI) is detected frequently in sera of patients with systemic non-thyroidal illness (NTI) (1–3). There is at present a paucity of information concerning the role of THBI in thyroid hormone abnormalities observed commonly in NTI. THBI appears to be a lipid moiety and unsaturated fatty acids are promising candidate THBIs (1). Serum concentrations of some unsaturated fatty acids (e.g., oleic acid) are markedly increased in NTI (4). In this study, we have examined the effect of the parenteral administration of unsaturated fatty acids on serum thyroid hormone and TSH concentrations in the rat.

Keywords

Oleic Acid Arachidonic Acid Unsaturated Fatty Acid Serum Thyroid Hormone Dialyzable Fraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Inder J. Chopra
    • 1
  • Tien-Shang Huang
    • 1
  • David H. Solomon
    • 1
  • Guadalupe N. Chua Teco
    • 1
  1. 1.Department of MedicineUCLA Center for the Health SciencesLos AngelesUSA

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