The Ionic Microscope Enables the Visualization of Stable Iodine within Follicles of the Human Thyroid Gland

  • Philippe Fragu
  • Eliane Larras-Regard


The functional characterization of thyroid cells is an important factor in thyroid tumor typing (1). This characterization should be possible with the development of cytochemical (2) and in situ hybridization techniques (3). Analytical ion microscopy (4,5), which is based on secondary ion spectrometry, makes possible an imaging of the distribution of a given stable or labeled element on a tissue section (6,7). The purpose of this study was to visualize stable iodine within the human thyroid follicle.


Thyroid Cancer Human Thyroid Ionic Microscope Hurthle Cell Cold Nodule 
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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Philippe Fragu
    • 1
  • Eliane Larras-Regard
    • 1
  1. 1.Inserm U.66Institut Gustave-RoussyVillejuifFrance

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