Preferential Metabolism of T4 to rT3 (T3 Reverse) in Hyperthyroxinemia Induced by L-Thyroxine (L-T4) Treatment of Hypothyroidism in Children and Adolescents
Preferential conversion to rT3, an inert metabolite of T4, has been proposed as a homeostatic mechanism for thyroid hormone inactivation in several physiopathological situations (1,2).
KeywordsHomeostatic Mechanism Hypothyroid Patient Inhibitory Dose Neonatal Thyroid Preferential Metabolism
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- 4.Guyda HJ. In GN Burrow and JH Dussault (eds), Neonatal Thyroid Screening, Raven Press, New York, 1980, p 247.Google Scholar
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