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Extrathyroidal Conversion of Thyroxine To 3,5,3’-Triiodothyronine in Rats Undergoing Acute Immobilization Stress

  • Antonio C. Bianco
  • Maria T. Nunes
  • Rui M. B. Maciel
  • Naomi S. Hell

Abstract

Several experimental and clinical conditions sharing stress as a common factor (i.e., fasting, surgical procedures, severe non-thyroidal systemic illnesses) are known to induce marked alterations on the extrathyroidal metabolism of iodothyronines (1). These alterations, known as the “low T3 syndrome,” are characterized by low 3,5,3’–triiodothyronine (T3), and high 3,3’,5’–triiodothyronine (rT3) serum concentrations, while thyroxine (T4) values in serum may be decreased or unchanged (2).

Keywords

Thyroid Hormone Bilateral Adrenalectomy Marked Alteration Kidney Homogenate Immobilization Period 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Antonio C. Bianco
    • 1
  • Maria T. Nunes
    • 1
  • Rui M. B. Maciel
    • 1
  • Naomi S. Hell
    • 1
  1. 1.Department of Physiology and Biophysics, Institute of Biomedical SciencesUniversity of Sao PauloSao PauloBrazil

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