The Neuroregulation of TSH and Prolactin Secretion
It is well known that the secretion of the anterior pituitary (AP) hormones, thyrotropin (TSH) and prolactin (PRL), is under tonic stimulatory and inhibitory control, respectively, by the hypothalamus. It is now clear also that the hypothalamic control of AP hormone secretion is mediated by the release into the portal blood vessels of a variety of peptidic and nonpeptidic substances. Data gathered during the last few years have demonstrated that TRH and the central neurotransmitter dopamine (DA) have important actions on TSH and PRL release from the AP. Furthermore, somatostatin and a variety of other central neurotransmitters such as noradrenaline have effects which will be considered briefly.
KeywordsThyroid Hormone Hypothyroid Animal TIDA Neuron Hypophyseal Portal Blood Anterior Pituitary Hormone Secretion
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