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Stimulation of Thyroid Adenylate Cyclase Activity in Sera of Patients with Nonthyroidal Illness

  • F. Kakezono
  • S. Yamashita
  • N. Yokoyama
  • S. Morita
  • S. Okamoto
  • I. Morimoto
  • N. Ikari
  • M. Izumi

Abstract

In assessing serum bioactive TSH, as measured by thyroid adenylate cyclase (TAC) stimulating activity, using the FRTL-5 cell line, we observed that sera from hypothyroid patients stimulated TAC. However, in our earlier studies, no correlation between TAC-stimulating activity and serum TSH or IgG was found. In the present study, TAC-stimulating activities were investigated in sera of patients with nonthyroidal illness (NTI).

Keywords

Thyroid Cell cAMP Concentration Hypothyroid Patient Nonthyroidal Illness Normal Serum Concentration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • F. Kakezono
    • 1
  • S. Yamashita
    • 1
  • N. Yokoyama
    • 1
  • S. Morita
    • 1
  • S. Okamoto
    • 1
  • I. Morimoto
    • 1
  • N. Ikari
    • 1
  • M. Izumi
    • 1
  1. 1.The First Department of Internal MedicineNagasaki University School of MedicineNagasakiJapan

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