Stimulation of Thyroid Adenylate Cyclase Activity in Sera of Patients with Nonthyroidal Illness
In assessing serum bioactive TSH, as measured by thyroid adenylate cyclase (TAC) stimulating activity, using the FRTL-5 cell line, we observed that sera from hypothyroid patients stimulated TAC. However, in our earlier studies, no correlation between TAC-stimulating activity and serum TSH or IgG was found. In the present study, TAC-stimulating activities were investigated in sera of patients with nonthyroidal illness (NTI).
KeywordsThyroid Cell cAMP Concentration Hypothyroid Patient Nonthyroidal Illness Normal Serum Concentration
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