Thyrotropic Activity of Acid Isoelectric Variants of Human Chorionic Gonadotropin from Trophoblastic Tumors
The occasional occurrence of hyperthyroidism in patients with trophoblastic diseases is widely unexplained and there is yet no proof that hCG is indeed the relevant thyrotropic factor (1,2). Therefore, we studied whether special tumor-derived forms of hCG with enhanced thyrotropic activity may exist.
KeywordsElectrophoresis Polyacrylamide Coomassie Hyperthyroidism Choriocarcinoma
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