Thyrotropic Activity of Acid Isoelectric Variants of Human Chorionic Gonadotropin from Trophoblastic Tumors

  • Klaus Mann
  • Norbert Schneider
  • Bernhard Saller
  • Rudolf Hoermann

Abstract

The occasional occurrence of hyperthyroidism in patients with trophoblastic diseases is widely unexplained and there is yet no proof that hCG is indeed the relevant thyrotropic factor (1,2). Therefore, we studied whether special tumor-derived forms of hCG with enhanced thyrotropic activity may exist.

Keywords

Electrophoresis Polyacrylamide Coomassie Hyperthyroidism Choriocarcinoma 

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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Klaus Mann
    • 1
  • Norbert Schneider
    • 1
  • Bernhard Saller
    • 1
  • Rudolf Hoermann
    • 1
  1. 1.Department of Internal Medicine IIKlinikum Grosshadern University of MunichGermany

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