Abstract
Phospholipid-dependent calcium-activated protein kinase, previously identified and termed protein kinase C (1), is known to be widely distributed among various tissues. Although many proteins can be substrates of protein kinase C, little is known about its physiological role. Diacylglycerol, a major degradative product of phosphatidylinositol (PI) turnover, was reported to stimulate protein kinase C in vitro (2). Previously, Igarashi and Kondo (3) have clearly shown that a transient increase of diacylglcerol is elicited by TSH in hog thyroid follicles. We, therefore, wished to know whether thyroid protein kinase C has a role in thyroid physiology. In the present paper, we report some aspects of protein kinase C in mouse thyroid lobes.
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© 1986 Springer Science+Business Media New York
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Haraguchi, K., Endo, T., Onaya, T. (1986). Effects of Phorbol Esters on Protein Phosphorylation and Free T3 Release by Mouse Thyroid Lobes. In: Medeiros-Neto, G., Gaitan, E. (eds) Frontiers in Thyroidology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5260-0_53
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DOI: https://doi.org/10.1007/978-1-4684-5260-0_53
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5262-4
Online ISBN: 978-1-4684-5260-0
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