Iodine Deficiency, the Thyroid, and the Brain

  • Basil S. Hetzel


The establishment of the essential link between iodine deficiency, thyroid function, and brain development has emerged over the past 20 years from a fascinating combination of clinical, epidemiological, and experimental studies.


Iodine Deficiency Endemic Goiter Iodine Deficiency Disorder Iodine Deficiency Disorder Spastic Diplegia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Konig MP. In BS Hetzel and RM Smith (eds), Fetal Brain Disorders, Elsevier Biomedical, Amsterdam, 1981, p 229.Google Scholar
  2. 2.
    McCarrison R. Lancet 2: 1275, 1908.CrossRefGoogle Scholar
  3. 3.
    McCullagh SF. Med J Aust 1: 769, 1963.Google Scholar
  4. 4.
    Choufoer JC, Van Rhijn M, and Querido A. J Clin Endocrinol 25: 385, 1965.CrossRefGoogle Scholar
  5. 5.
    Pharoah POD, Delange F, Fierro-Benitez R, et al. In JB Stanbury and BS Hetzel (eds), Endemic Goiter and Endemic Cretinism, Wiley, New York, 1980, p 395.Google Scholar
  6. 6.
    Wespi HJ. Schweiz Md Wochenschr 75: 625, 1945.Google Scholar
  7. 7.
    Costa A, Cottino F, Mortara M, et al. Panminerva Med 6: 250, 1964.Google Scholar
  8. 8.
    Buttfield IH and Hetzel BS. Bull WHO 36: 243, 1967.PubMedGoogle Scholar
  9. 9.
    Buttfield IH and Hetzel BS. Aust Ann Med 18: 217, 1969.PubMedGoogle Scholar
  10. 10.
    Pharoah POD, Buttfield IH, and Hetzel BS. Lancet 1: 308, 1971.PubMedCrossRefGoogle Scholar
  11. 11.
    Hetzel BS, Thilly CH, Fierro-Beintez R, et al. In JB Stanbury and BS Hetzel (eds), Endemic Goiter and Endemic Cretinism, Wiley, New York, 1980, p 513.Google Scholar
  12. 12.
    Connolly KC, Pharoah POD, and Hetzel BS. Lancet 2: 1149, 1979.PubMedCrossRefGoogle Scholar
  13. 13.
    Potter BJ, Mano MT, Belling GB, et al. Neuropathol Appl Neurobiol 8: 303, 1982.PubMedCrossRefGoogle Scholar
  14. 14.
    Hetzel BS and Potter BJ. In IE Dreosti and RM Smith (eds), Neurobiology of the Trace Elements, Humana Press, New Jersey, 1983, p 45.Google Scholar
  15. 15.
    McIntosh GH, Potter BJ, Mano MT, et al. Neuropathol Appl Neurobiol 9: 215, 1983.PubMedCrossRefGoogle Scholar
  16. 16.
    Obregon MJ, Mallol J, Pastor R, et al. Endocrinol 114: 305, 1984.CrossRefGoogle Scholar
  17. 17.
    Woods RJ, Sinha AK, and Ekins, RP. Clin Sci 67: 359, 1984.PubMedGoogle Scholar
  18. 18.
    Pharoah POD, Connolly KJ, Ekins RP, et al. Cl Endo 21: 265, 1984.CrossRefGoogle Scholar
  19. 19.
    Hetzel BS. Lancet 2: 1126, 1983.PubMedCrossRefGoogle Scholar
  20. 20.
    WHO/SEARO. A Regional Strategy for the Control of Iodine Deficiency Disorders in Countries of the SE Asian Region. WHO/SEARO, Delhi, 1985.Google Scholar
  21. 21.
    Tai M, Tizhang L, Uybin R, et al. Food Nutr Bull 4: 13, 1982.Google Scholar
  22. 22.
    Control of Iodine Deficiency in Asia. Lancet 2: 1244, 1983.Google Scholar

Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Basil S. Hetzel
    • 1
  1. 1.CSIRO Division of Human NutritionAdelaideSouth Australia

Personalised recommendations