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Defective TSH Suppression in a Case of Non-Neoplastic Inappropriate TSH Secretion (ITSHS)

  • Salvatore Benvenga
  • Giuseppe A. Sobbrio
  • Francesco Vermiglio
  • Salvatore Cannavo
  • Antonio Granata
  • Gaetano Lombardi
  • Francesco Trimarchi

Abstract

The non-neoplastic inappropriate secretion of thyroid stimulating hormone (ITSHS) classification (1) includes also defective suppression of TSH secretion by somatostatin, dopamine, and other suppressors. These abnormalities have been postulated but not yet, at least contemporarily, documented in any reported case. The present study demonstrates the defective suppression of TSH secretion by dopamine, dopamine agonists, somatostatin, and corticosteroids, and also reports the measurement of plasma immunoreactive endogenous thyrotropin-releasing hormone (TRH) in a patient with ITSHS and thyroid hormone resistance (2).

Keywords

Thyroid Hormone Pituitary Adenoma Dopamine Agonist Partial Target Thyroid Hormone Resistance 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Salvatore Benvenga
    • 1
  • Giuseppe A. Sobbrio
    • 1
  • Francesco Vermiglio
    • 1
  • Salvatore Cannavo
    • 1
  • Antonio Granata
    • 1
  • Gaetano Lombardi
    • 2
  • Francesco Trimarchi
    • 1
  1. 1.Instituto di Clinica Medica e Terapia MedicaUniversity of MessinaPoliclinico, MessinaItaly
  2. 2.Instituto di Scienze EndocrinologicheUniversity of NaplesItaly

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