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Comparison of a Pituitary TSH-Secreting Micro- Versus Macroadenoma

  • Neil Gesundheit
  • Patricia A. Petrick
  • Terry Taylor
  • Edward H. Oldfield
  • Bruce D. Weintraub

Abstract

While more than 40 cases of TSH-secreting pituitary adenomas have been reported in the medical literature (1,2), little attention has been devoted to structural variability—in particular that due to carbohydrate microheterogeneity—of thyrotropin molecules derived from different tumors and distinct physiological states. We recently evaluated two patients representing extremes within the spectrum of TSH-secreting pituitary adenomas and have contrasted several biochemical features of these tumors.

Keywords

Pituitary Adenoma Apparent Molecular Weight Carbohydrate Structure Computer Tomographic Pituitary Fossa 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Neil Gesundheit
    • 1
  • Patricia A. Petrick
    • 1
  • Terry Taylor
    • 1
    • 2
  • Edward H. Oldfield
    • 3
  • Bruce D. Weintraub
    • 1
  1. 1.Molecular, Cellular and Nutritional Endocrinology Branch,National Institute of Arthritis, Diabetes, and Digestive and Kidney DiseasesNational Institutes of HealthBethesdaUSA
  2. 2.Surgical Neurology Branch, National Institute of Neurological and Communicative Disorders and StrokeNational Institutes of HealthBethesdaUSA
  3. 3.Georgetown University School of MedicineUSA

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