Comparison of a Pituitary TSH-Secreting Micro- Versus Macroadenoma
While more than 40 cases of TSH-secreting pituitary adenomas have been reported in the medical literature (1,2), little attention has been devoted to structural variability—in particular that due to carbohydrate microheterogeneity—of thyrotropin molecules derived from different tumors and distinct physiological states. We recently evaluated two patients representing extremes within the spectrum of TSH-secreting pituitary adenomas and have contrasted several biochemical features of these tumors.
KeywordsPituitary Adenoma Apparent Molecular Weight Carbohydrate Structure Computer Tomographic Pituitary Fossa
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