Neonatal Hypothyroid Screening: Nationwide Experience in Japan
Our initial motivation for this study was, of course, to identify the patients with congenital hypothyroidism and treat them as early as possible. Klein et al. (1) have shown that mental retardation can be prevented if the patient is treated at an early stage. Clinical diagnosis is often difficult except in severe cases with quite typical signs and symptoms, and this is often too late for effective treatment to prevent mental retardation. A screening test is, therefore, thought to be necessary.
KeywordsCongenital Hypothyroidism Neonatal Screening Primary Hypothyroidism Maple Syrup Urine Disease Ectopic Thyroid
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