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Iodine-Sufficient Goiter and Autoimmune Thyroiditis: The Kentucky and Colombian Experience

  • Eduardo Gaitan

Abstract

Thyroid disorders constitute today a significant public health problem in Colombia, S.A. and in the United States (1,2). Goiter continues to occur in some areas despite adequate iodine supplementation. For instance, a continued high prevalence of goiter in many localities of western Colombia, as well as in the coal-rich Appalachian area of eastern Kentucky, has been reported (1,2). The incidence of lymphocytic autoimmune thyroiditis (AT) has has steadily increased in the U.S. during the past five decades and it has been attributed to iodine prophylaxis and excessive iodine intake (2). In western Colombia, S.A., where iodine prophylaxis was instituted thirty years ago, a similar trend has been documented (3). However, lymphocytic infiltration was of high degree in most of the U.S. glands, while it was minimal in 70% of the Colombian cases. Thus, recent studies were designed to reassess and gain insight into the problem of goiter and AT in areas of eastern Kentucky and western Colombia, where goiter persists despite iodine supplementation. Nearby localities where goiter has not been a problem were similarly investigated.

Keywords

Humic Substance Iodine Deficiency Subclinical Hypothyroidism Autoimmune Thyroiditis Phthalate Ester 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Eduardo Gaitan
    • 1
  1. 1.Administration Medical CenterUniversity of Mississippi Medical School and VeteransJacksonUSA

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