Bovine Thyrotropin Binding Sites in Nuclei and Nuclear Matrix of Porcine Thyrocytes
Thyrotropin (TSH) stimulates its thyroid target cells by interacting with specific receptors on the membrane (1). TSH binding sites have been purified and characterized in human and animal thyroid tissue using crude broken cell preparations, purified membranes, or whole cells (1,2). Our immunocytochemical studies, at light microscopical level, documented TSH binding sites intracellularly in porcine thyrocytes, particularly at the nuclear membrane and within the nucleus (2,3).
KeywordsNuclear Membrane Nuclear Matrix Light Microscopical Level Radioreceptor Assay Gold Particle Size
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