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Isolation of a Gene Encoding Human Thyrotropin Beta Subunit

  • G. Kerr Whitfield
  • Robin E. Powers
  • James A. Gurr
  • Ofra Wolf
  • Ione A. Kourides

Abstract

Thyrotropin (TSH) is a member of the family of glycoprotein hormones which also includes the pituitary gonadotropins, lueteinizing hormone and follicle-stimulating hormone, and the placental chorionic gonadrotropin. Each of these hormones is composed of dissimilar, non-convalently interacting, glycosylated subunits called α and β. Within a species, the α subunits are identical, and the β subunit determines the biologic and immunologic specificity of the complete hormone (1).

Keywords

Glycoprotein Hormone Glycoprotein Hormone Subunit Human RAT1 Mouse Apparent Signal Peptide Human Parental Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • G. Kerr Whitfield
    • 1
  • Robin E. Powers
    • 1
  • James A. Gurr
    • 1
  • Ofra Wolf
    • 1
  • Ione A. Kourides
    • 1
  1. 1.Laboratory of Molecular EndocrinologyMemorial Sloan-Kettering Cancer CenterNew YorkUSA

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