Growth Control of Follicular Cells in Vitro

  • F. S. Ambesi-Impiombato
  • D. Tramontano
  • B. M. Veneziani


Thyroid follicular cells represent a fine example of endocrine and hormone-regulated cells. Similar to other types, both cell growth and differentiation are exactly adjusted in vivo throughout the life of the organism. Regulation of cell proliferation and acquisition and maintenance of the differentiated phenotype seem part of the unique program coordinated under normal conditions and subverted by pathological conditions leading to tumor growth and anaplastic dedifferentiation.


Follicular Cell Thyroid Cell Mitogenic Stimulation Primary Follicle Thyroid Follicular Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Doniach D, Bottazzo GF, and Khoury EL. In A Pinchera, D Doniach, GF Fenzi, et al. (eds), Autoimmune Aspects of Endocrine Disorders, Academic Press, London, 1980, p 25.Google Scholar
  2. 2.
    Tong W, Kerkof P, and Chaikoff IL. Biochim Biophys Acta 60: 1, 1962.PubMedCrossRefGoogle Scholar
  3. 3.
    Rapaport B and Adams RJ. J Biol Chem 251: 6653, 1976.Google Scholar
  4. 4.
    Rapaport B. Endocrinology 98: 1189, 1976.CrossRefGoogle Scholar
  5. 5.
    Winand RJ and Kohn LD. J Biol Chem 250: 6534, 1975.PubMedGoogle Scholar
  6. 6.
    O11is CA, Munro DS, and Tomlinson S. J Endocrinol 95: 237, 1982.PubMedCrossRefGoogle Scholar
  7. 7.
    Fayet G, Hovsepian S, Dickson JC, et al. J Cell Biol 93: 479, 1982.PubMedCrossRefGoogle Scholar
  8. 8.
    Wadeleux PA, Etienne-Decerf J, Winand RJ, et al. Endocrinology 102: 889, 1978.PubMedCrossRefGoogle Scholar
  9. 9.
    Westermark B, Karlsson FA, and Walinder O. Proc Natl Acad Sci USA 76: 2022, 1979.PubMedCrossRefGoogle Scholar
  10. 10.
    Roger PR and Dumont JE. FEBS Lett 144: 209, 1982.PubMedCrossRefGoogle Scholar
  11. 11.
    Roger PP, Servais P, and Dumont JE. FEBS Lett 157: 323, 1983.PubMedCrossRefGoogle Scholar
  12. 12.
    Bachrach LK, Eggo MC, Mak WW, et al. In MC Eggo and GN Burrow (eds), Thyroglobulin - The Prothyroid Hormone, Raven Press, New York, Vol. 2, 1985, p 263.Google Scholar
  13. 13.
    Roger PR and Dumont JE. J Endocrinol 96: 241, 1983.PubMedCrossRefGoogle Scholar
  14. 14.
    Roger PR and Dumont JE. Mol Cell Endocrinol 36: 79, 1984.PubMedCrossRefGoogle Scholar
  15. 15.
    Westermark K, Karlsson FA, Ericson LE, et al. In MC Eggo and GN Burrow (eds), Thyroglobulin - The Prothyroid Hormone, Raven Press, New York, Vol. 2, 1985, p 255.Google Scholar
  16. 16.
    Ullrich A, Bell JR, Chen EY, et al. Nature 313: 756, 1985.PubMedCrossRefGoogle Scholar
  17. 17.
    Ebina Y, Ellis L, Jarnagin K, et al. Cell 40: 747, 1985.PubMedCrossRefGoogle Scholar
  18. 18.
    Perrotti N, Taylor SI, Richert ND, et al. Science 227: 761, 1985.PubMedCrossRefGoogle Scholar
  19. 19.
    Robbins KC, Antoniades HN, Devare SG, et al. Nature 305: 605, 1983PubMedCrossRefGoogle Scholar
  20. 20.
    Downward J, Yarden Y, Mayes E, et al. Nature 307: 521, 1984.PubMedCrossRefGoogle Scholar
  21. 21.
    Inoue K, Horiuchi R, and Kondo Y. Endocrinology 107: 1162, 1980.PubMedCrossRefGoogle Scholar
  22. 22.
    Nitsch L and Wollman SH. Proc Natl Acad Sci USA 77: 472, 1980.PubMedCrossRefGoogle Scholar
  23. 23.
    Mauchamp JA, Margotat M, Chambard B, et al. Cell Tissue Res 204: 417, 1979.PubMedCrossRefGoogle Scholar
  24. 24.
    Nitsch L and Wollman SH. Proc Natl Acad Sci USA 77: 2747, 1980.Google Scholar
  25. 25.
    Ambesi-Impiombato FS, Parks LAM, and Coon HG. Proc Natl Acad Sci USA 77: 3455, 1980.CrossRefGoogle Scholar
  26. 26.
    Ambesi-Impiombato FS,Picone R, and Tramontano D. Cold Spring Harbor Conf on Cell Prolif 9: 483, 1982.Google Scholar
  27. 27.
    Avivi A, Tramontano D, Ambesi-Impiombato FS, et al. Mol Cell Endocrinol 25: 55, 1982.PubMedCrossRefGoogle Scholar
  28. 28.
    Tramontano D, Avivi A, Ambesi-Impiombato FS, et al. Exp Cell Res 137: 269, 1982.PubMedCrossRefGoogle Scholar
  29. 29.
    Valente WA, Vitti P, Kohn LD, et al. Endocrinology 112: 71, 1983.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • F. S. Ambesi-Impiombato
    • 2
  • D. Tramontano
    • 1
  • B. M. Veneziani
    • 1
  1. 1.Centro di Endocrinologia ed Oncologia Sperimentale del CNR Dipartimento di Biologia e Patologia Cellulare e Molecolare II Facolta di Medicina e ChirurgiaUniversita di NapoliNaplesItaly
  2. 2.Instituto di Biochimica-Fiscia e Patologia Cellulare e MolecolareFacolta di Medicina e Chirurgia di Catanzaro Universita di Reggio CalabriaCatanzaroItaly

Personalised recommendations