Studies on the Effects of Thyroid Hormones and their Metabolites on Human Red Cell Acetylcholine Esterase
The activity of acetylcholine esterase of human red cells was studied in the presence or absence of thyroid hormones and their metabolites such as L-T1, L-T2, L-T3, and L-T4. The activity of the enzyme of intact red cells was not affected by these hormones, though studied under various conditions: the activity of acetylcholine esterase of intact red cells was 19.5 ± 1.2 units/gHb in the absence of L-T1, and 18.3 ± 0.9 units/gHb and 19.8 ± 1.4 units/gHb in the presence of 50 μg/dl and 500 μg/dl of L-T1, respectively. Similarly, 3,5-L-T2, 3,3-L-T2, rT3, L-T3, and L-T4 had little effect on the enzyme activity of intact red cells.
KeywordsThyroid Hormone Acetylcholine Esterase Pathophysiological Significance 2central Clinical Laboratory Acetylcholine Esterase Activ
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