Insulin Deficiency Impairs Thyroid Peroxidase Activity: A Study in Experimental Diabetes Mellitus

  • Egberto G. Moura
  • Carmen C. Pazos
  • Doris Rosenthal


Various abnormalities of thyroid function have been described in diabetes mellitus. Clinical, as well as subclinical, hypothyroidism have been shown to occur with increased frequency in insulin-dependent diabetes (1). Alloxan or streptozotocin (STZ)-induced diabetes is associated with a decrease in basal and TSH-stimulated thyroid function in animals (2,3).


Experimental Diabetes Thyroid Uptake Experimental Diabetes MELLITUS Iodine Organification 131I Thyroid 
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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Egberto G. Moura
    • 1
  • Carmen C. Pazos
    • 1
  • Doris Rosenthal
    • 1
  1. 1.Instituto de Biologia, UERJInstituto de Biofisica, UFRJRio de JaneiroBrazil

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