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Selective Inhibition by Monoamine Oxidase (MAO) Inhibitors of the Iodotyrosine Formation Induced by MAO Substrates in Bovine Thyroid Tissue

  • Ana M. Masini-Repiso
  • Ana M. Cabanillas
  • Marta C. Andrada

Abstract

Monoamine oxidase (EC 1.4.3.4) (MAO) may probably be involved in the hydrogen peroxide generation required for the iodination process in the thyroid tissue (1,2). Biogenic amines have been demonstrated to be able to generate hydrogen peroxide and to increase iodine organification in thyroid tissue, and these effects were decreased by MAO inhibitors (3,4). On the other hand, it was observed that rat thyroid MAO activity was increased by TSH administration and reduced after hypophysectomy (2).

Keywords

Monoamine Oxidase Biogenic Amine Thyroid Tissue Generate Hydrogen Peroxide Common Substrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Ana M. Masini-Repiso
    • 1
  • Ana M. Cabanillas
    • 1
  • Marta C. Andrada
    • 1
  1. 1.Catedra de Quimica Clinica I, Facultad de Ciencias QuimicasUniversidad Nacional de CordobaCordobaArgentina

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