Emerging Concepts in Inherited Disorders of Thyroid Metabolism

  • Geraldo Medeiros-Neto


Congenital disorders of thyroid metabolism may result from complete or partial blockage at any biochemical step in hormone synthesis, storage, secretion, delivery, or utilization. Our understanding of inborn errors of thyroid awaited the development of sophisticated biochemical investigative tests pioneered by Stanbury just over 35 years ago (1). Since then, there has been an enormous growth of our knowledge of these disorders. The detailed molecular mechanism in each defect has been only partially elucidated but progress in this field has greatly assisted our knowledge of normal thyroid physiology.


Thyroid Hormone Multinodular Goiter Thyroxine Binding Globulin Goiter Prevalence Thyroid Metabolism 
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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Geraldo Medeiros-Neto
    • 1
  1. 1.Thyroid LaboratoryHospital das Clinicas University of Sao Paulo Medical SchoolSao PauloBrazil

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