Regulation of the Yeast CYC1 Gene

  • Leonard P. Guarente
Part of the Basic Life Sciences book series (BLSC, volume 40)


Evidence is increasingly accumulating to indicate that eukaryotic RNA polymerases do not recognize promoter sequences encoded in DNA as does their prokaryotic counterpart. Rather, eukaryotic promoter/regulatory regions encompass sites that bind multiple transcription factors. Some of these factors are “mechanical” in nature, such as the TATA box factor required for genes transcribed by RNA polymerase II. Other factors are gene-specific and bind to sequences found upstream of the TATA box. The interplay of the latter class of factors with regulatory sequences is responsible for regulation of transcription.


Initiation Site CYCI Gene TATA Element Yeast Promoter Nonfermentable Carbon Source 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Leonard P. Guarente
    • 1
  1. 1.Department of BiologyMassachusetts Institute of TechnologyCambridgeUSA

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