Abstract
By virtue of the ecological niches they occupy, protozoa have ample opportunity to become infected with virus-like particles (VLPs). One of the better described and documented instances of such an infection is in Entamoeba histolytica, an endosymbiont of the human gut. Diamond and co-workers (2) have described several different VLPs in the nucleus and cytoplasm of Entamoeba, but the source of infection is not clear. These VLPs may have been acquired by the amebas during their residence in the intestinal lumen, an ideal habitat for numerous species of bacteria and viruses. Not resolved in this study is the relationship between the VLPs and the ability of Entamoeba to cause amebic dysentery. Does the presence of VLPs in the ameba serve as a means of enhancing virulence of the amebas? The VLPs apparently cause lysis of amebas under appropriate circumstances (2).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Cerva, L. (1969) Amoebic meningoencephalitis: Axenic culture of Naegleria. Science 163:576.
Diamond, L.S., and C.F.T. Mattern (1976) Protozoal viruses. In Advances in Virus Research, M.A. Laufer et al., eds. Academic Press, Inc., New York, pp. 87–112.
Dunnebacke, T.H., and F.L. Schuster (1971) Infectious agent from a free-living soil amoeba, Naegleria gruberi. Science 174:516–518.
Dunnebacke, T.H., and F.L. Schuster (1977) The nature of a cytopathogenic material present in amebae of the genus Naegleria. Am. J. Trop. Med. Hyg. 26:412–421.
Dunnebacke, T.H., and F.L. Schuster (1985) Morphological response of cultured cells to Naegleria amoeba cytopathogenic material. J. Cell Sci. 75:1–16.
Grornan, N.B. (1984) Conversion by corynephages and its role in the natural history of diphtheria. J. Hyg. Camb. 93:405–417.
Hammar, S.P., D. Bockus, F. Remington, and S. Friedman (1984) More on ultrastructure of AIDS lymph nodes. New Engl. J. Med. 310:924.
John, D.T. (1982) Primary amebic meningoencephalitis and the biology of Naegleria fovleri. Ann. Rev. Microbiol. 36:101–123.
Kostianovsky, M., and P.M. Grimley (1985) Ultrastructural findings in the acquired immunodeficiency syndrome (AIDS). Ultrastructural Pathol. 8:123–130.
Martinez, A.J. (1985) Free-Living Amebas: Natural History, Prevention, Diagnosis, Pathology, and Treatment of Disease, CRC Press, Inc., Boca Raton, Florida.
Preer, Jr., J.R., and L.B. Preer (1967) Virus-like bodies in killer paramecia. Proc. Natl. Acad. Sci., USA 58:1774–1781.
Prineas, J.W., and R.G. Wright (1978) Macrophages, lymphocytes, and plasma cells in the perivascular compartment in chronic multiple sclerosis. Lab. Investigation 38:409–421.
Schuster, F.L. (1969) Intranuclear virus-like bodies in the amoeboflagellate Naegleria gruberi. J. Protozool. 16:724–727.
Schuster, F.L., and J.S. Clemente (1977) 5-Bromodeoxyuridine-induced formation of virus-like particles in Naegleria gruberi EGS. J. Cell Sci. 26:359–371.
Schuster, F.L., and T.H. Dunnebacke (1971) Formation of bodies associated with virus-like particles in the amoeboflagellate Naegleria gruberi. J. Ultrastructure Res. 36:659–668.
Schuster, F.L., and T.H. Dunnebacke (1974) Virus-like particles and an unassociated infectious agent in amoebae of the genus Naegleria. Ann. Soc. Belge Med. Trop. 54:359–370.
Schuster, F.L., and T.H. Dunnebacke (1976) Development and release of virus-like particles in Naegleria gruberi EGS. Cytobiologie 14:131–147.
Sidhu, G.S. (1983) Ultrastructure of AIDS lymph nodes. New Engl. J. Med. 309:1188–1189.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Plenum Press, New York
About this chapter
Cite this chapter
Schuster, F.L., Dunnebacke, T.H. (1986). Virus-Like Particles in a Soil Ameboflagellate, Naegleria Gruberi . In: Wickner, R.B., et al. Extrachromosomal Elements in Lower Eukaryotes. Basic Life Sciences, vol 40. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5251-8_27
Download citation
DOI: https://doi.org/10.1007/978-1-4684-5251-8_27
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5253-2
Online ISBN: 978-1-4684-5251-8
eBook Packages: Springer Book Archive