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Use of Fluorescent Fatty Acids for Labelling Acid Lipase-Deficient Cells

  • A. Nègre
  • A. Maret
  • R. Salvayre
  • G. Farré
  • L. Douste-Blazy
  • S. Gatt
Part of the NATO ASI Series book series (NSSA, volume 116)

Abstract

Wolman’s disease1,2 and cholesterol ester storage diseases3–5 are two hereditary lysosomal disorders characterized by a severe deficiency of acid lipase activity2,3,5–7 and a major lysosomal accumulation of cholesteryl esters and triglycerides3,4, which can be demonstrated by lipid analysis or microscopic examination3.

Keywords

Cholesteryl Ester Decanoic Acid Acid Lipase Human Leukemic Myeloid Cell Lysosomal Acid Lipase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • A. Nègre
    • 1
  • A. Maret
    • 1
  • R. Salvayre
    • 1
  • G. Farré
    • 2
  • L. Douste-Blazy
    • 1
  • S. Gatt
    • 3
  1. 1.Faculté de MédecineLaboratoire de Biochimie and INSERM 101ToulouseFrance
  2. 2.Laboratoire de BiologieFaculté de MédecineToulouseFrance
  3. 3.Dept of Membrane Biochemistry and NeurochemistryHebrew University-Hadassah School of MedicineJerusalemIsrael

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