Metabolism of Inositol-Glycerophospholipids in Relation to Transmembrane Signalling and Calcium Mobilization

  • Hugues Chap
  • Philippe Dajeans
  • Josette Fauvel
  • Gérard Mauco
  • Monique Plantavid
  • Line Rossignol
  • Marie-Françoise Simon
  • Louis Douste-Blazy
Part of the NATO ASI Series book series (NSSA, volume 116)

Abstract

Since the discovery by Hokin and Hokin1,2 of an increased turnover of phosphatidylinositol triggered in pigeon pancreatic slices by cholinergic agonists, inositol-phospholipids have been the matter of a large number of studies, which were extensively reviewed in 1975 by Miche113. In the last three years, this field gained a renewed interest starting from a series of fundamental and complementary findings, which allow to understand how inositol-phospholipid metabolism is directly linked to the mechanism of transmembrane signalling. These very new concepts were recently reviewed in several excellent papers4–7.

Keywords

Sponge Cytosol Acetylcholine Fibrinogen Vasopressin 

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Hugues Chap
    • 1
  • Philippe Dajeans
    • 1
  • Josette Fauvel
    • 1
  • Gérard Mauco
    • 1
  • Monique Plantavid
    • 1
  • Line Rossignol
    • 1
  • Marie-Françoise Simon
    • 1
  • Louis Douste-Blazy
    • 1
  1. 1.Biochimie des Lipides, Hôpital PurpanINSERM Unité 101ToulouseFrance

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